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Clinical reviews
INDIRECT TREATMENT COMPARISON BETWEEN FIXED-DOSE-COMBINATIONS OF AMLODIPINE/LOSARTAN AND AMLODIPINE/VALSARTAN IN BLOOD PRESSURE CONTROL
A. Lawrence Gould, S. Unniachan, D. Wu
PDF201310 pages185 KB
The research involved a systematic search that identified six randomized controlled trials comparing the efficacy of amlodipine/losartan and amlodipine/valsartan. The primary focus was on the changes in sitting diastolic and systolic blood pressure after 8 weeks of treatment. The findings suggest that while both combinations are effective, there are slight differences in blood pressure reduction between the two fixed-dose combinations. This study provides valuable insights for clinicians in choosing antihypertensive therapies.
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