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David M. Kent, MD, MS; Andy Y. Wang, MD
A patent foramen ovale (PFO) is an opening between the right and left atria that is present in about 25% of adults and can lead to paradoxical embolism, contributing to approximately 5% of all strokes. The review discusses the significance of PFO in younger patients and highlights the Risk of Paradoxical Embolism (RoPE) score, which helps predict the likelihood of stroke in patients with PFO. The document synthesizes current evidence regarding the management of PFO in the context of stroke prevention.
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