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John W. Winkelman, MD, PhD; Benjamin Wipper, MD
Restless legs syndrome (RLS) affects approximately 3% of US adults and can significantly impair quality of life. The disorder is characterized by an urge to move the legs, often leading to sleep disturbances. The review details the prevalence of RLS in various populations, including those with multiple sclerosis, kidney disease, and during pregnancy. It also discusses treatment options, emphasizing the use of gabapentinoids over dopaminergic agents due to the risk of symptom augmentation with long-term use.
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