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Clinical reviews
RISK FOR BLEEDING-RELATED HOSPITALIZATIONS DURING USE OF AMIODARONE WITH APIXABAN OR RIVAROXABAN IN PATIENTS WITH ATRIAL FIBRILLATION
Annals of Internal Medicine
PDF202311 pages217 KB
The research is a retrospective cohort study focusing on U.S. Medicare beneficiaries aged 65 years or older. It compares the incidence of bleeding-related hospitalizations among patients treated with amiodarone versus those treated with antiarrhythmic drugs that do not inhibit anticoagulant elimination. The findings indicate a significant increase in the risk of bleeding-related events associated with the use of amiodarone in conjunction with these anticoagulants.
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