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Clinical reviews
UPDATES FOR CARDIO- KIDNEY PROTECTIVE EFFECTS BY ANGIOTENSIN RECEPTOR- NEPRILYSIN INHIBITOR: REQUIREMENT FOR ADDITIONAL EVIDENCE OF KIDNEY PROTECTION
City University
PDF14 pages785 KB
The review highlights the increasing incidence of heart failure and chronic kidney disease, emphasizing the role of ARNI as a promising therapeutic option. It compares the cardioprotective effects of ARNI with traditional renin-angiotensin system inhibitors (RAS-Is) and discusses findings from major clinical trials, including PARADIGM-HF and UK HARP-III. The authors suggest that while ARNI may offer benefits for both cardiac and renal health, its renoprotective effects may be limited to specific patient populations.
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